Details for gene set NCI_TGF-BETA RECEPTOR SIGNALING[GSEA]

Table: GSEA Results Summary

Dataset	set03_truncNotch_versus_normalThy
Phenotype	NoPhenotypeAvailable
Upregulated in class	na_neg
GeneSet	NCI_TGF-BETA RECEPTOR SIGNALING
Enrichment Score (ES)	-0.48339587
Normalized Enrichment Score (NES)	-1.8674273
Nominal p-value	0.0
FDR q-value	0.06799437
FWER p-Value	0.672

Table: GSEA details [plain text format]
	PROBE	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	CEBPB	39	9.502	0.0113	No
2	IL5	45	9.359	0.0243	No
3	MAPKAPK2	58	8.591	0.0358	No
4	CDK4	86	7.778	0.0454	No
5	FGR	143	7.022	0.0523	No
6	EIF4EBP1	268	6.109	0.0542	No
7	EEF2K	289	5.954	0.0615	No
8	BAD	784	4.120	0.0405	No
9	PIAS3	979	3.746	0.0352	No
10	HSPB1	990	3.722	0.0399	No
11	EGR3	1068	3.569	0.0408	No
12	IL2RA	1123	3.488	0.0428	No
13	MYC	1180	3.415	0.0446	No
14	MAP3K7IP1	1199	3.378	0.0484	No
15	BLK	1301	3.219	0.0475	No
16	USF1	1464	3.021	0.0429	No
17	CDC25B	1519	2.963	0.0442	No
18	ARRB2	1536	2.944	0.0475	No
19	RBBP4	1624	2.853	0.0468	No
20	TP53	1734	2.750	0.0447	No
21	DAB2	1770	2.714	0.0467	No
22	CDKN1A	1821	2.661	0.0477	No
23	PPP1CA	1885	2.600	0.0480	No
24	TCF3	2016	2.484	0.0444	No
25	DUSP10	2057	2.463	0.0457	No
26	PRKACA	2114	2.419	0.0461	No
27	IL4	2334	2.280	0.0374	No
28	MAP3K10	2364	2.261	0.0390	No
29	FKBP8	2409	2.232	0.0398	No
30	SHC1	2417	2.229	0.0426	No
31	RUNX3	2418	2.228	0.0457	No
32	SLC3A2	2671	2.093	0.0350	No
33	MAPK3	2925	1.958	0.0240	No
34	RBBP7	3007	1.925	0.0223	No
35	ITGB5	3044	1.908	0.0230	No
36	IL10	3140	1.863	0.0205	No
37	RNF128	3148	1.861	0.0227	No
38	YWHAQ	3313	1.791	0.0163	No
39	PKN1	3396	1.761	0.0144	No
40	GRB2	3538	1.714	0.0091	No
41	CTDSP1	3599	1.690	0.0082	No
42	RPS6KA4	3689	1.664	0.0058	No
43	RUNX2	3706	1.658	0.0072	No
44	COL1A2	3772	1.638	0.0060	No
45	SERPINE1	3851	1.612	0.0040	No
46	CALM1	3948	1.579	0.0011	No
47	E2F1	4079	1.545	-0.0038	No
48	ETV1	4288	1.484	-0.0131	No
49	TGIF2	4345	1.467	-0.0140	No
50	NKX2-5	4390	1.455	-0.0144	No
51	EIF4E	4842	1.338	-0.0370	No
52	ESR1	5304	1.220	-0.0604	No
53	LYN	5368	1.203	-0.0622	No
54	CDKN2B	5729	1.115	-0.0802	No
55	TBX21	5746	1.112	-0.0795	No
56	ATF1	5760	1.109	-0.0786	No
57	IFNB1	5849	1.085	-0.0819	No
58	PRKCZ	5893	1.076	-0.0827	No
59	ATF3	6265	0.994	-0.1015	No
60	SNTA1	6327	0.979	-0.1034	No
61	MAP3K6	6399	0.965	-0.1059	No
62	CAV1	6478	0.945	-0.1088	No
63	MAPK13	6583	0.919	-0.1132	No
64	CTGF	6609	0.915	-0.1133	No
65	DLX1	6672	0.896	-0.1154	No
66	ZBTB17	6780	0.872	-0.1200	No
67	TAOK2	6927	0.840	-0.1267	No
68	PARD6A	7311	0.759	-0.1465	No
69	SAP18	7432	0.735	-0.1520	No
70	PTPN1	7537	0.714	-0.1567	No
71	MAPKAPK5	7540	0.713	-0.1558	No
72	PRKCA	7649	0.691	-0.1607	No
73	XPO1	7829	0.653	-0.1695	No
74	HCK	7871	0.643	-0.1708	No
75	RAN	8046	0.606	-0.1794	No
76	TH	8138	0.583	-0.1836	No
77	CCND1	8140	0.583	-0.1828	No
78	NR4A1	8191	0.573	-0.1847	No
79	VDR	8273	0.557	-0.1883	No
80	SOS1	8457	0.519	-0.1976	No
81	CITED1	8487	0.511	-0.1984	No
82	DUSP8	8517	0.504	-0.1993	No
83	MAPK12	8571	0.491	-0.2015	No
84	MAP3K4	8643	0.476	-0.2047	No
85	AKT1	8696	0.467	-0.2068	No
86	PPARG	8728	0.461	-0.2079	No
87	NR3C1	8735	0.461	-0.2075	No
88	HNF4A	8772	0.454	-0.2089	No
89	CTBP1	8868	0.429	-0.2134	No
90	IL2	9059	0.390	-0.2232	No
91	CSF2	9327	0.329	-0.2373	No
92	GADD45G	9370	0.321	-0.2391	No
93	SMAD7	9750	0.233	-0.2594	No
94	CASP3	9967	0.184	-0.2709	No
95	PRKCE	10026	0.168	-0.2739	No
96	PAK3	10035	0.165	-0.2741	No
97	RIPK1	10351	0.086	-0.2911	No
98	MAP2K3	10472	0.051	-0.2976	No
99	PPARGC1A	10520	0.038	-0.3001	No
100	FOS	10770	-0.029	-0.3136	No
101	IL3	10817	-0.043	-0.3160	No
102	TNF	10851	-0.051	-0.3178	No
103	YWHAZ	10875	-0.059	-0.3189	No
104	EGR4	10880	-0.060	-0.3191	No
105	PRKCH	11098	-0.114	-0.3307	No
106	AR	11203	-0.146	-0.3362	No
107	STMN1	11411	-0.206	-0.3472	No
108	SKIL	11504	-0.235	-0.3518	No
109	FOSL1	11626	-0.268	-0.3581	No
110	YES1	11724	-0.298	-0.3629	No
111	MAPKAPK3	11729	-0.299	-0.3627	No
112	CAMK2B	11809	-0.327	-0.3666	No
113	FOXH1	11896	-0.349	-0.3707	No
114	PTGS2	11918	-0.354	-0.3714	No
115	STRAP	11928	-0.360	-0.3714	No
116	MYOD1	11963	-0.369	-0.3727	No
117	GSC	12061	-0.397	-0.3774	No
118	CD40LG	12191	-0.434	-0.3838	No
119	PRKCD	12195	-0.435	-0.3834	No
120	MEF2C	12220	-0.444	-0.3840	No
121	NFATC2	12258	-0.453	-0.3854	No
122	BAMBI	12283	-0.460	-0.3861	No
123	ZFYVE9	12294	-0.465	-0.3860	No
124	YWHAE	12605	-0.561	-0.4021	No
125	RPS6KA5	12623	-0.567	-0.4022	No
126	TFDP1	12684	-0.584	-0.4046	No
127	FOXO3	12713	-0.594	-0.4053	No
128	JUN	12736	-0.603	-0.4056	No
129	OCLN	12781	-0.621	-0.4072	No
130	SKI	12814	-0.633	-0.4080	No
131	DACT2	12854	-0.644	-0.4092	No
132	NUP153	12857	-0.645	-0.4084	No
133	PLA2G4A	13012	-0.699	-0.4158	No
134	CAMK2A	13297	-0.813	-0.4301	No
135	FOXG1	13372	-0.842	-0.4330	No
136	MEF2D	13381	-0.847	-0.4322	No
137	RAC1	13414	-0.858	-0.4327	No
138	IFNG	13438	-0.868	-0.4328	No
139	SRC	13590	-0.923	-0.4397	No
140	MAP3K5	13604	-0.929	-0.4391	No
141	RAB5A	13643	-0.942	-0.4398	No
142	ELK4	13777	-1.001	-0.4456	No
143	TSC2	13804	-1.010	-0.4456	No
144	MAP3K7	13920	-1.056	-0.4504	No
145	DYNLRB1	13962	-1.073	-0.4511	No
146	ZFYVE16	14180	-1.177	-0.4612	No
147	YAP1	14203	-1.189	-0.4608	No
148	GADD45B	14233	-1.204	-0.4606	No
149	SNIP1	14242	-1.207	-0.4594	No
150	PRKG1	14283	-1.226	-0.4598	No
151	MAP2K4	14296	-1.233	-0.4587	No
152	CAMK4	14327	-1.247	-0.4586	No
153	SFN	14447	-1.307	-0.4632	No
154	CSNK2A1	14622	-1.386	-0.4707	No
155	DAXX	14635	-1.395	-0.4694	No
156	CTLA4	14652	-1.403	-0.4683	No
157	DDIT3	14712	-1.439	-0.4694	No
158	YWHAB	14792	-1.481	-0.4717	No
159	CSNK1A1	14797	-1.485	-0.4698	No
160	DUSP1	14879	-1.529	-0.4720	No
161	RALB	14911	-1.551	-0.4715	No
162	SLC9A1	14952	-1.574	-0.4715	No
163	PAK1	15056	-1.632	-0.4748	No
164	RALA	15090	-1.655	-0.4742	No
165	MITF	15122	-1.675	-0.4735	No
166	RPS6KB1	15174	-1.716	-0.4739	No
167	MAX	15243	-1.769	-0.4751	No
168	MKNK1	15297	-1.800	-0.4754	No
169	UBE2I	15301	-1.803	-0.4730	No
170	ATM	15302	-1.803	-0.4705	No
171	SMAD3	15332	-1.826	-0.4694	No
172	E2F5	15561	-1.994	-0.4790	No
173	LCK	15642	-2.053	-0.4805	Yes
174	YWHAG	15675	-2.080	-0.4793	Yes
175	CBLB	15678	-2.083	-0.4764	Yes
176	CREBBP	15702	-2.106	-0.4747	Yes
177	MAP3K7IP2	15735	-2.133	-0.4734	Yes
178	KPNB1	15749	-2.141	-0.4711	Yes
179	NCOR1	15773	-2.164	-0.4693	Yes
180	PIAS4	15885	-2.263	-0.4721	Yes
181	RAF1	16017	-2.394	-0.4759	Yes
182	IRF4	16037	-2.419	-0.4735	Yes
183	HDAC2	16088	-2.468	-0.4727	Yes
184	HDAC1	16133	-2.512	-0.4715	Yes
185	PTPRK	16140	-2.524	-0.4683	Yes
186	CREB1	16167	-2.549	-0.4661	Yes
187	CALM2	16239	-2.624	-0.4663	Yes
188	RBL1	16274	-2.655	-0.4643	Yes
189	GATA3	16277	-2.658	-0.4607	Yes
190	PML	16283	-2.663	-0.4572	Yes
191	KPNA2	16310	-2.686	-0.4548	Yes
192	CTDSPL	16334	-2.711	-0.4522	Yes
193	FKBP1A	16523	-2.958	-0.4583	Yes
194	SAP30	16538	-2.975	-0.4548	Yes
195	HSPA8	16541	-2.979	-0.4507	Yes
196	MAPK8	16556	-2.993	-0.4472	Yes
197	PAK2	16651	-3.116	-0.4479	Yes
198	MAPK14	16698	-3.190	-0.4459	Yes
199	JUNB	16800	-3.351	-0.4467	Yes
200	SIN3B	16802	-3.352	-0.4420	Yes
201	TGFBR1	16864	-3.455	-0.4404	Yes
202	POU2F1	16867	-3.457	-0.4356	Yes
203	SMURF2	16913	-3.523	-0.4331	Yes
204	NCOA2	16939	-3.555	-0.4294	Yes
205	CBFB	16989	-3.629	-0.4269	Yes
206	MAPK1	17133	-3.886	-0.4292	Yes
207	SRF	17174	-3.958	-0.4258	Yes
208	YWHAH	17289	-4.152	-0.4261	Yes
209	TRAF2	17307	-4.186	-0.4211	Yes
210	SIN3A	17309	-4.192	-0.4152	Yes
211	MAP3K8	17320	-4.218	-0.4098	Yes
212	PPM1A	17322	-4.226	-0.4038	Yes
213	MAP3K3	17391	-4.397	-0.4013	Yes
214	RUNX1	17402	-4.421	-0.3956	Yes
215	FYN	17414	-4.454	-0.3899	Yes
216	ATF2	17460	-4.560	-0.3859	Yes
217	PIM1	17464	-4.569	-0.3796	Yes
218	CALM3	17473	-4.587	-0.3735	Yes
219	GSK3B	17591	-4.835	-0.3730	Yes
220	FASLG	17629	-4.926	-0.3681	Yes
221	SP1	17636	-4.943	-0.3614	Yes
222	PRKCQ	17644	-4.969	-0.3547	Yes
223	MEF2A	17651	-5.007	-0.3480	Yes
224	CDK2	17662	-5.028	-0.3414	Yes
225	SMAD2	17670	-5.039	-0.3346	Yes
226	ITCH	17735	-5.234	-0.3307	Yes
227	LSP1	17753	-5.292	-0.3241	Yes
228	MAP2K6	17779	-5.369	-0.3179	Yes
229	TRAF6	17804	-5.432	-0.3115	Yes
230	MAP3K1	17806	-5.436	-0.3038	Yes
231	RNF111	17847	-5.551	-0.2981	Yes
232	PPP2CA	17858	-5.604	-0.2908	Yes
233	PPP2CB	17874	-5.668	-0.2835	Yes
234	CCM2	17885	-5.688	-0.2760	Yes
235	MAP3K12	17894	-5.720	-0.2684	Yes
236	FOXP3	17901	-5.743	-0.2605	Yes
237	MAPK9	17946	-5.900	-0.2546	Yes
238	NCOA1	17974	-6.035	-0.2475	Yes
239	RHOA	17985	-6.067	-0.2395	Yes
240	MAPK11	18122	-6.671	-0.2374	Yes
241	EGR1	18190	-7.067	-0.2310	Yes
242	TGFBR2	18294	-7.848	-0.2255	Yes
243	NFATC1	18298	-7.855	-0.2146	Yes
244	NFATC3	18304	-7.953	-0.2036	Yes
245	PDPK1	18310	-8.013	-0.1925	Yes
246	SMAD4	18320	-8.095	-0.1815	Yes
247	TGFBR3	18368	-8.522	-0.1720	Yes
248	AXIN1	18371	-8.558	-0.1600	Yes
249	GDI1	18384	-8.666	-0.1484	Yes
250	CTDSP2	18401	-8.819	-0.1367	Yes
251	GADD45A	18439	-9.374	-0.1255	Yes
252	HBP1	18488	-10.231	-0.1136	Yes
253	DUSP16	18511	-10.949	-0.0993	Yes
254	DGKA	18512	-10.953	-0.0838	Yes
255	BCL2	18517	-11.183	-0.0681	Yes
256	NEDD4L	18518	-11.213	-0.0522	Yes
257	LAMC1	18559	-13.236	-0.0357	Yes
258	EGR2	18610	-27.324	0.0003	Yes